MR measurement of increased concentrations of choline containing compounds (tCho) in the liver could be used as a non-invasive tumor tissue biomarker. However, 3D 1H-MRSI with conventional water suppression and volume selection does not yield the sensitivity gain expected at higher fields like 7T. As a result, it cannot be performed in clinically feasible scan times with full coverage of the liver and at sufficient spatial resolution to detect tumor metastases. With spectral-spatial pulses, it is possible to spatially map tCho much faster and at higher SNR than with conventional MRSI, with excellent suppression of both water and lipid signals.
This abstract and the presentation materials are available to members only; a login is required.