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Abstract #0917

RF-encoding for improved multi-voxel separation in MR spectroscopy

Adam Berrington1, Penny Gowland1, and Richard Bowtell1
1Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom

The simultaneous acquisition and separation of signals from multiple voxels using receive sensitivities can accelerate MRS acquisition. However, separation is ill-conditioned when signals are acquired from voxels with similar receive-coil sensitivities. We propose a new approach which improves reconstruction using the transmitted RF to modulate the signals from different voxels. Simulations showed that for a small number of encoding steps, M, the g-factor of the reconstruction problem was reduced (~3-fold, M=2 for 5 regions). Reconstructed phantom data from two-voxels, acquired using phase-modulation, were of higher SNR than coil-encoding, indicating the potential of the proposed method for multi-voxel measurement in MRS.

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