The simultaneous acquisition and separation of signals from multiple voxels using receive sensitivities can accelerate MRS acquisition. However, separation is ill-conditioned when signals are acquired from voxels with similar receive-coil sensitivities. We propose a new approach which improves reconstruction using the transmitted RF to modulate the signals from different voxels. Simulations showed that for a small number of encoding steps, M, the g-factor of the reconstruction problem was reduced (~3-fold, M=2 for 5 regions). Reconstructed phantom data from two-voxels, acquired using phase-modulation, were of higher SNR than coil-encoding, indicating the potential of the proposed method for multi-voxel measurement in MRS.
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