Abstract #0946

The value of preoperative prediction of ki67 and P53 expression in DCE-MRI texture analysis of rectal cancer

Yuhui Liu¹, Ailian Liu¹, and Mingxiao Wang¹

¹The First Affiliated Hospital of Dalian Medical University, Dalian, China, Dalian, China

This study aims to analyze the intrinsic relationship between imaging indicators and tumor biological behavior, and improve the clinical value of DCE-MRI.The correlation between DCE-MRI quantitative parameter values (Ktrans, Ve, Kep) and molecular biomarkers (Ki67,P53) was compared and explored in patients with rectal cancer.(Ki67:the combined diagnostic performance is obtained,the AUC was 0.923, with the sensitivity of 90.5% and the specificity of 50%.P53:the combined diagnostic performance is obtained,the AUC was 0.737, with the sensitivity of 72.7% and the specificity of 66.7%.)

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.