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Abstract #0960

Ultrahigh Field Cardiac MRI in a Large Animal Model of Acute and Chronic Infarction

David Lohr1, Maya Bille1, Maxim Terekhov1, Michael Hock1, Ibrahim Elabyad1, Steffen Baltes1, Alena Kollmann1, Theresa Reiter1,2, Florian Schnitter2, Wolfgang Rudolf Bauer1,2, Ulrich Hofmann2, and Laura Maria Schreiber1
1Chair of Molecular and Cellular Imaging, Comprehensive Heart Failure Center (CHFC), University Hospital Würzburg, Würzburg, Germany, 2Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany

Ultrahigh field cardiac MRI in a large animal model with acute and chronic infarction is feasible and enables high resolution functional imaging with 4- to 16-fold higher in-plane resolution compared to clinical systems. Blood-tissue contrast enabled clear identification of tissue boundaries, papillary muscle and the valves. Apical slices were akinetic. Mean values for ejection fraction [%] at baseline and 3-4, 10-14, and 60 days post MI were: 66±5, 45±7, 49±10, 50±5, respectively. Coefficients of variation for intra- and inter-observer variability in ejection fraction were 1.5% and 6.2%. T2*-weighted images and LGE enabled visualization of the infarct area.

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