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Abstract #0963

Feature tracking derived global early diastolic longitudinal strain rate in risk stratification of HFpEF:A preliminary prognostic study

Jian He1, Gang Yin1, Weichun Wu2, and Minjie Lu1
1Department of Magnetic Resonance Imaging, Fuwai Hospital & Cardiovascular Institute, Chinese Academy of Medical Sciences & Tsinghua University, Peking Union Medical College, National Center for Cardiovascular Diseases, beijing, China, 2Department of Ultrasound, Fuwai Hospital & Cardiovascular Institute, Chinese Academy of Medical Sciences & Tsinghua University, Peking Union Medical College, National Center for Cardiovascular Diseases, beijing, China

In this retrospective study, 167 HFpEF patients (median age 60 years, 40% women) were included. At a median follow-up of 110 (IQR 104–120) months, 71 patients experienced the primary composite outcome of all-cause death and HF hospitalization. Impaired global early diastolic longitudinal strain rate (eGLSR), defined as an eGLSR < median, 0.57/s, was present in 49.7% of patients and was predictive of the composite outcome (adjusted HR 2.57, 95% CI 1.58–4.45; p=0.001), and HF hospitalization alone (adjusted HR 2.48, 95% CI 1.31–4.70; p=0.005) after adjusting for clinical and conventional imaging variables.

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