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Abstract #0963

Feature tracking derived global early diastolic longitudinal strain rate in risk stratification of HFpEF：A preliminary prognostic study

Jian He1, Gang Yin1, Weichun Wu2, and Minjie Lu1
1Department of Magnetic Resonance Imaging, Fuwai Hospital & Cardiovascular Institute, Chinese Academy of Medical Sciences & Tsinghua University, Peking Union Medical College, National Center for Cardiovascular Diseases, beijing, China, 2Department of Ultrasound, Fuwai Hospital & Cardiovascular Institute, Chinese Academy of Medical Sciences & Tsinghua University, Peking Union Medical College, National Center for Cardiovascular Diseases, beijing, China

In this retrospective study, 167 HFpEF patients (median age 60 years, 40% women) were included. At a median follow-up of 110 (IQR 104–120) months, 71 patients experienced the primary composite outcome of all-cause death and HF hospitalization. Impaired global early diastolic longitudinal strain rate (eGLSR), defined as an eGLSR < median, 0.57/s, was present in 49.7% of patients and was predictive of the composite outcome (adjusted HR 2.57, 95% CI 1.58–4.45; p=0.001), and HF hospitalization alone (adjusted HR 2.48, 95% CI 1.31–4.70; p=0.005) after adjusting for clinical and conventional imaging variables.

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Abstract