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Abstract #0989

Myocardial fibrosis in preserved ejection fraction hypertrophic cardiomyopathy: predictive values of non-invasive markers

Yumin Li1, Xiaoyue Zhou2, Jia Liu1, Yukun Cao1, Xiaoyu Han1, Guozhu Shao1, Jin Gu1, Tong Liu1, Na Li1, Yue Cui1, and Heshui Shi1
1Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 2MR Collaboration, Siemens Healthineers Ltd, ShangHai, China

This study aimed to determine the predictive value of non-invasive markers in patients with hypertrophic cardiomyopathy with preserved ejection fraction. The results demonstrated that an elevated level of N-terminal pro b-type natriuretic peptide (Nt-proBNP) was an independent predictor for the presence of late gadolinium enhancement (LGE), and combined with maximum wall thickness (MWT), had good diagnostic performance for the detection of LGE. Furthermore, decreased left ventricular global circumferential strain (GCS) was independently correlated with the LGE%, indicating its potential prognostic value for detecting myocardial fibrosis.

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