Elastography in MRI (MRE) and ultrasound (USE) are the most reliable imaging techniques for liver fibrosis detection. However, there is no established, standardized material that mimics the elasticity and viscous behavior of liver tissue and can be used as a phantom for MRE and USE. We developed a phantom based on polyacrylamide which shows a viscoelastic dispersion from 5-3000 Hz similar to that observed in the healthy human liver, which is measurable by MRE and USE, stable over months and can be produced in a reproducible way. The novel phantom facilitates technical improvements and cross-modality comparisons in MRE and USE.
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