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Abstract #1019

Optimal multiple motion encoding in phase contrast MRI

Helge Herthum1, Hugo Carrillo2, Axel Osses2, Sergio Uribe3, Ingolf Sack1, and Cristóbal Bertoglio4
1Experimentelle Radiologie, Charité Universitätsmedizin Berlin, Berlin, Germany, 2Center for Mathematical Modeling, Universidad de Chile, Santiago, Chile, 3Department of Radiology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile, 4Bernoulli Institute, University of Groningen, Groningen, Netherlands

Optimal multiple motion encoding (OMME) for phase-contrast MRI was developed with application to magnetic resonance elastography for unwrapping motion images. OMME is formulated as a least-squares problem using multiple phase-contrast measurements with different motion encoding gradients (MEG). OMME is applied to phantom and in vivo human brain experiments. The wrap-free motion images are further used to reconstruct shear-wave-speed maps and compared to conventional phase unwrapping methods. OMME generates wrap free phase-contrast images with the wrap limit determined by the smallest MEG used, while maintaining the signal-to-noise ratio(SNR) of the largest MEG, which makes OMME especially suitable for high SNR applications.

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