Pancreatic Magnetic Resonance Elastography (MRE) allows non-invasive estimation of pancreatic tissue visco-elastic properties for multiple pathophysiological diseases. The aim of this study is to optimize pancreatic GRE-MRE to provide an in-depth analysis of the propagation and registration of shear waves. Optimization was performed using four combinations of frequency, the number of measured wave-phase offsets, and TE. Pancreas GRE-MRE at 40Hz, TE 6.9ms and 4 or 5 wave-phase offsets can estimate the SWS of the pancreas head with optimal encoding and propagation and has an acceptable breath-hold duration for clinical purposes.
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