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Abstract #1021

Optimization of GRE-MRE in the pancreas 

Anne-Sophie van Schelt1, Nienke Wassenaar1, Eric M Schrauben1, Marian Troelstra1,2, Jules L. Nelissen1, Ralph Sinkus2,3, Jaap Stoker4, Aart J Nederveen1, and Jurgen H Runge1
1Radiology and Nuclear Medicine, Amsterdam UMC location AMC, Amsterdam, Netherlands, 2Department of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom, 3Inserm U1148, LVTS, University Paris Diderot, Paris, France, 4Radiology and Nuclear medicine, Amsterdam UMC location AMC, Amsterdam, Netherlands

Pancreatic Magnetic Resonance Elastography (MRE) allows non-invasive estimation of pancreatic tissue visco-elastic properties for multiple pathophysiological diseases. The aim of this study is to optimize pancreatic GRE-MRE to provide an in-depth analysis of the propagation and registration of shear waves. Optimization was performed using four combinations of frequency, the number of measured wave-phase offsets, and TE. Pancreas GRE-MRE at 40Hz, TE 6.9ms and 4 or 5 wave-phase offsets can estimate the SWS of the pancreas head with optimal encoding and propagation and has an acceptable breath-hold duration for clinical purposes.

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