In diffusion weighted imaging, multi-shot Echo Planar Imaging (EPI) is preferred over single-shot EPI due to reduced geometric distortion. Recent work has shown that low-rank reconstructions can correct ghosts from shot-to-shot phase without explicitly acquiring a phase navigator. These works have been limited to EPI sampling trajectories with uniform ky sampling. 2D Cartesian Fast Spin Echo (FSE) is a distortionless alternative to multi-shot EPI that has greater freedom in k-space traversal and reduced chemical shift artifacts. Using FSE, we demonstrate in simulation and in vivo that an intelligent choice of sampling pattern greatly enhances image quality in multi-shot diffusion imaging.
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