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Abstract #1312

Whole-brain Diffusion Tensor Imaging Using Single-Shot Spiral Sampling

Guangqi Li1, Xin Shao1, Xinyu Ye1, Xiaodong Ma2, and Hua Guo1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2Center for Magnetic Resonance Research, Radiology, Medical School, University of Minnesota, Minneapolis, MN, United States

Single-shot acquisition techniques are commonly used to acquire diffusion weighted images. Single-shot spiral sampling allows shorter TE acquisition, thus provides higher SNR compared to EPI acquisition. However, spiral acquisition is sensitive to field inhomogeneity. Blurring effects degrade the quality of spiral images. In this study, compared to previous studies, a relatively large acceleration factor was used to reduce the spiral readout duration, and off-resonance correction was implemented for deblurring. The results show that the proposed single-shot spiral sampling can achieve whole-brain diffusion tensor imaging.

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