Abstract #1326

Optimising spiral diffusion tensor cardiovascular magnetic resonance for high resolution ex-vivo STEAM imaging on a clinical scanner

Malte Roehl^1,2, Peter D Gatehouse^1,2, Pedro F Ferreira^1,2, Sonya V Babu-Narayan^1,2, David N Firmin^1,2, Dudley J Pennell^1,2, Sonia Nielles-Vallespin^1,2, and Andrew D Scott^1,2

¹National Heart and Lung Institute, Imperial College London, London, United Kingdom, ²Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, United Kingdom

We demonstrate STEAM spiral diffusion tensor cardiovascular magnetic resonance (DT-CMR) for high resolution ex-vivo imaging (1x1x2mm²) on a clinical 3T scanner. We optimized the coil combination method, diffusion weighting, number of spiral interleaves and averages. A comparison in ex-vivo porcine myocardium shows substantial improvements in image quality when using the spiral method over a single-shot STEAM EPI protocol acquired with matched duration, spatial resolution and diffusion encoding.

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