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Abstract #1326

Optimising spiral diffusion tensor cardiovascular magnetic resonance for high resolution ex-vivo STEAM imaging on a clinical scanner

Malte Roehl1,2, Peter D Gatehouse1,2, Pedro F Ferreira1,2, Sonya V Babu-Narayan1,2, David N Firmin1,2, Dudley J Pennell1,2, Sonia Nielles-Vallespin1,2, and Andrew D Scott1,2
1National Heart and Lung Institute, Imperial College London, London, United Kingdom, 2Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, United Kingdom

We demonstrate STEAM spiral diffusion tensor cardiovascular magnetic resonance (DT-CMR) for high resolution ex-vivo imaging (1x1x2mm2) on a clinical 3T scanner. We optimized the coil combination method, diffusion weighting, number of spiral interleaves and averages. A comparison in ex-vivo porcine myocardium shows substantial improvements in image quality when using the spiral method over a single-shot STEAM EPI protocol acquired with matched duration, spatial resolution and diffusion encoding.

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