Current approaches for motion correction of quantitative MRI include model-driven registration (MDR) and model-free registration (MFR). This study compared MDR against a state-of-the-art groupwise MFR (GMFR) on T1-mapping, DTI and DCE from 10 patients with diabetic kidney disease. The results demonstrate the benefits of MDR in the context of quantitative imaging: MDR scores better on most quality and error metrics (up to 20% improvement) and offers a substantial gain in computation times (up to 17hrs per slice). Furthermore, there is potential for translation to other applications.
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