Abstract #1450

Initial Results of a Novel High-Resolution 3D-FSE Based Protocol for Silicone Breast Implant Screening

Tayeb Zaidi¹, John Mugler², Maureen Hood³, Brian Garra⁴, Erin Kelly⁵, Hung Do⁵, Mo Kadbi⁵, and Sunder Rajan¹

¹Division of Biomedical Physics, Food and Drug Administration, Silver Spring, MD, United States, ²Department of Radiology and Medical Imaging Research, University of Virginia, Charlottesville, VA, United States, ³Department of Radiology & Radiological Sciences, Uniformed Services University, Bethesda, MD, United States, ⁴Division of Imaging, Diagnostics, and Software Reliability, Food and Drug Administration, Silver Spring, MD, United States, ⁵Canon Medical Systems USA, Tustin, CA, United States

Conventional silicone breast MR involves multi-contrast 2D scans. However, the use of 2D imaging risks the loss of fine structure visualization in the 3rd dimension. An isotropic 3D-FSE pulse sequence was first tested in a single-center study in 13 subjects with silicone breast implants (SBI). The images were evaluated by radiologists for quality and added utility of the bilateral, 3D scans. To allow for multi-site implementation of the 3D sequence, a bilateral breast phantom containing lipid, fibroglandular mimic and a silicone implant was tested across major MR vendors to ensure adequate signal-to-noise ratios and tissue contrast.

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