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Abstract #1450

Initial Results of a Novel High-Resolution 3D-FSE Based Protocol for Silicone Breast Implant Screening

Tayeb Zaidi1, John Mugler2, Maureen Hood3, Brian Garra4, Erin Kelly5, Hung Do5, Mo Kadbi5, and Sunder Rajan1
1Division of Biomedical Physics, Food and Drug Administration, Silver Spring, MD, United States, 2Department of Radiology and Medical Imaging Research, University of Virginia, Charlottesville, VA, United States, 3Department of Radiology & Radiological Sciences, Uniformed Services University, Bethesda, MD, United States, 4Division of Imaging, Diagnostics, and Software Reliability, Food and Drug Administration, Silver Spring, MD, United States, 5Canon Medical Systems USA, Tustin, CA, United States

Conventional silicone breast MR involves multi-contrast 2D scans. However, the use of 2D imaging risks the loss of fine structure visualization in the 3rd dimension. An isotropic 3D-FSE pulse sequence was first tested in a single-center study in 13 subjects with silicone breast implants (SBI). The images were evaluated by radiologists for quality and added utility of the bilateral, 3D scans. To allow for multi-site implementation of the 3D sequence, a bilateral breast phantom containing lipid, fibroglandular mimic and a silicone implant was tested across major MR vendors to ensure adequate signal-to-noise ratios and tissue contrast.

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