MT and CEST characteristics of DU145 prostate tumour xenografts with known responses to radiation treatment were investigated to determine characteristics that may predict treatment response. After excision for histology, tumours were categorized according to their response to treatment (responder, partial responder and non-responder). Average MTR, qMT parameters, and CEST and rNOE contributions were calculated for each category. Significant changes were mostly observed in the necrotic/apoptotic regions of the tumour and were most evident in the qMT parameters. It may be possible to determine efficacy early on in the course of treatment based on the studied MR characteristics.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords