Abstract #1484

Differential diagnosis rectal cancer with and without lymph node metastasis using amide proton transfer-weighted imaging and T1 map

Anliang Chen¹, Ailian Liu¹, Jiazheng Wang², Zhiwei Shen², Deshuo Dong¹, Wan Dong¹, Yuhui Liu¹, Qingwei Song¹, and Renwang Pu¹

¹Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China, ²Philips Healthcare, Beijing, China

Amide proton transfer-weighted (APTw) imaging can be used to assess changes of intracellular protein concentration and the pH value. Non-invasive visualization and quantification of tissue composition could be detected by T1 map. In this study, we aim to explore the value in difference of rectal cancer with and without lymph node metastasis using APTw imaging combined with T1 map. High diagnostic efficacy (AUC: 0.891; sensitivity: 81.8%; specificity: 100.0%) was achieved with combination of APT and T1 values.

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