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Abstract #1541

Reproducibility of 3D MR Fingerprinting with Different Dictionary Resolution in the Healthy Human Brain

Krishna Pandu Wicaksono1, Yasutaka Fushimi1, Satoshi Nakajima1, Akihiko Sakata1, Takuya Hinoda1, Sonoko Oshima1, Sayo Otani1, Hiroshi Tagawa1, Yang Wang1, Tomohisa Okada1, and Yuji Nakamoto1
1Kyoto University, Graduate School of Medicine, Kyoto, Japan

3D MR Fingerprinting was introduced as a rapid quantitative MRI technique, enabling higher SNR efficiency and spatial resolution than the 2D counterpart. As a crucial element of MRF reconstruction, the impact of dictionary resolution on MRF performance is essential to be investigated. Following our phantom study, which determined equivalent accuracy and repeatability of 3D MRF using two different dictionary resolutions, a reproducibility study in healthy volunteers was performed. This study demonstrated a comparable 3D MRF reproducibility from two different dictionary resolutions in most brain parenchyma. Yet, lower reproducibility was evident in CSF measurement, more obviously in a higher resolution dictionary.

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