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Abstract #1552

Myocardial T1, T2, T2* and Fat Fraction Quantification via Low-Rank Motion-Corrected Cardiac MRF

Gastao Cruz1, Carlos Velasco1, Olivier Jaubert1, Haikun Qi1, René M. Botnar1, and Claudia Prieto1
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Cardiac Magnetic Resonance Fingerprinting (MRF) has been proposed for simultaneous myocardial T1, T2 and fat fraction quantification using ECG-triggering, mid-diastolic acquisition window and a 3-echo gradient echo sequence. Here we extend this framework to further enable T2* quantification. This is achieved with an 8-echo sequence with increased acquisition window (to acquire sufficient data within a breath-hold) and a low-rank motion correction reconstruction to correct for cardiac motion within this increased window. The proposed approach enables simultaneous mapping of T1, T2, T2* and fat fraction within a single breath-hold with similar quality to conventional (sequential) single parameter approaches.

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