It is important to accurately identify carotid necrotic core (NC), intraplaque hemorrhage (IPH) due to its strong association with ischemic stroke. Multi-contrast cardiovascular magnetic resonance (CMR) vessel wall imaging has become an effective non-invasive technique to assess carotid plaque components. The aim of this study sought to confirm criteria of signal intensity threshold of all plaque components by comparing multiple tissue references validated by histology. This study afforded a standard of the signal intensity threshold ratio of carotid plaque components compared to reference tissues on multi-contrast cardiovascular MR imaging, and provides the basis for accurate identification of crucial plaque components.
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