To investigate the effects of chronic exposure to cigarette smoke or electronic cigarette aerosol on the vascular endothelium, various MRI parameters were examined in an ongoing study involving healthy young people (mean age<30y). Peripheral, cerebrovascular reactivity, and central aortic stiffness were evaluated comparing smokers (N=11) and vapers (N=15) to their nonsmoking-peers (N=31). There were no significant differences between groups, but hyperemic blood flow acceleration trended lower in smokers/vapers while arterial stiffness trended higher in smokers, relative to nonsmokers. The findings may suggest that exposure in these young subjects was not be sufficient to cause measurable adverse effects on the endothelium.
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