Abstract #1633

Developmental trajectories of cerebral blood flow and neurodevelopmental score in preterm children from 28 days to 13 years

Peiyao Chen¹, Chao Jin¹, Xianjun Li¹, Miaomiao Wang¹, Congcong Liu¹, Xiaoyu Wang¹, Fan Wu¹, Yuli Zhang¹, Cong Tian¹, Mengxuan Li¹, Xiaocheng Wei², and Jian Yang¹

¹First Affiliated Hospital of Xi 'an Jiaotong University, Xi'an, Shaanxi, China, ²MR Research China, GE Healthcare, Beijing, China

Preterm children often accompany undesirable neurodevelopmental outcomes. Adequate cerebral blood flow (CBF) is essential to brain development and function. However, little is known about relationship among preterm birth, CBF and neurodevelopmental outcome. This study aims to investigate the effect of preterm birth on CBF and explore the relationship between CBF and neurodevelopmental score. Our results suggest that the effects of preterm birth on intellectual development are long lasting and extend even into late childhood. After controlling for age, CBF shows positive correlations with mental and psychomotor development indexes in left frontal and occipital lobes in preterm children.

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