We developed and refined a novel method, Variable TI, to improve the visibility of ASL based UTE 4D-MRA. From numerical simulations and the flow phantom studies we found the signal tendency and blood signal skipping phenomena. With refined parameters we got 50% of signal enhancement comparing to conventional method. We conduct volunteer study with the refined Variable TI UTE 4D-MRA and this novel method offered a higher signal intensity and improved visualization of arteries in late phase compared to the conventional method. The Variable TI technique can improve clinical usability of 4D-MRA.
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