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Abstract #1671

Power spectral density of salience network alterations in obsessive-compulsive disorder: Impact on thought-action fusion performance

Eunji Kim1, Sang Won Lee2, Hyunsil Cha1, Heajung Choi1, Seungho Kim1, Yunheung Kim3, Seung Jae Lee2, and Yongmin Chang4
1Medical & Biological Engineering, Kyungpook National University, Daegu, Korea, Republic of, 2Psychiatry, Kyungpook National University Hospital, Daegu, Korea, Republic of, 3Kyungpook National University, Daegu, Korea, Republic of, 4Radiology and Molecular Medicine, Kyungpook National University, Daegu, Korea, Republic of

Obsessive-compulsive disorder (OCD) showed the functional connectivity alterations in default mode network (DMN), central executive network (CEN) and salience network (SN) 1. We investigated the difference of intrinsic networks between OCD and healthy controls (HC) from thought-action fusion (TAF) task and resting state by using fMRI. During TAF task, Power spectral density (PSD) of SN in OCD showed lower than PSD in HC in low-frequency bins. PSD of SN showed a significant correlation with TAF score and OBQ scale in OCD. Therefore when doing TAF task, OCD symptoms might have relations with alterations of PSD of SN.

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