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Abstract #1683

Preliminary Assessment of Intravoxel Incoherent Motion Diffusion-Weighted MRI Metrics in Acute Carbon Monoxide Poisoning

Shenghai Wang1, Juan Chen1, Kechao Xu1, Xiyao Zhang1, Haining Li2, and Zhengxian Zhang1
1Yan 'an People's Hospital, Yan 'an, China, 2First Affiliated Hospital of Xi 'an Jiaotong University, Xi 'an, China

The purpuse of this study was to assess microvascular perfusion and microstructural integrity using Intravoxel incoherent motion (IVIM) imaging in patients with acute CO poisoning.Thirteen patients with acute CO poisoning and 15 healthy subjects were enrolled. IVIM MRI was collected using a 3.0-T scanner.The ROIs analysis was perforemed. The IVIM perfusion fraction was significantly reduced in multiple brain regions and IVIM diffusion metirc was significantly decreased in centrum semiovale and multiple subcortical gray matter nucleis in CO poisoning. This study shows that IVIM-DWI may be a promising method to assess brain perfusion and injury in acute CO poisoning.

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