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Abstract #1689

Resting-state functional connectivity and brain network abnormalities in depressive patients with suicidal ideation

Jun-Cheng Weng1,2,3, Yu-Syuan Chou4, Yuan-Hsiung Tsai5,6, and Vincent Chin-Hung Chen3,5
1Department of Medical Imaging and Radiological Sciences, and Bachelor Program in Artificial Intelligence, Chang Gung University, Taoyuan, Taiwan, 2Medical Imaging Research Center, Institute for Radiological Research, Chang Gung University and Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, 3Department of Psychiatry, Chang Gung Memorial Hospital, Chiayi, Taiwan, 4Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan, 5School of Medicine, Chang Gung University, Taoyuan, Taiwan, 6Department of Diagnostic Radiology, Chang Gung Memorial Hospital, Chiayi, Taiwan

Our study aimed to investigate whether changes in brain function measured with functional magnetic resonance imaging (fMRI) can be detected among individuals with depressive disorders and suicidal ideation, including amplitude of low-frequency fluctuation (ALFF), regional homogeneity (ReHo), and graph theoretical analysis (GTA). We results suggest that brain functional connectivity may be affected in depressive patients with suicidal ideation. The findings from present study can serve as the basis for further algorithm studies by machine learning method to stratify the risk population.

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