Abstract #1748

Long-term cognitive and neurological Effects of COVID-19 Illness detected by 7T MRI

Helma Heidari^1,2, Stephanie Handsor³, Koula Pantazopoulos⁴, Lauryn Richardson⁴, Kristy Coleman⁴, Michael Silverman⁵, Erin Spicer³, Stephen Pasternak^4,6, Luciano Sposato⁶, Doug Fraser⁷, Anthony Tang⁸, Ravi S. Menon^1,2, Corey Baron^1,2, Michael Jurkiewicz⁹, Elizabeth Finger^4,6, Marko Mrkobrada³, Megan Devlin³, and Robert Bartha^1,2

¹Robarts research Institute, London, ON, Canada, ²Medical Biophysics, The University of Western Ontario, London, ON, Canada, ³Internal Medicine, The University of Western Ontario, London, ON, Canada, ⁴Parkwood Institute, London, ON, Canada, ⁵Infectious Diseases, The University of Western Ontario, London, ON, Canada, ⁶Clinical Neurological Sciences, The University of Western Ontario, London, ON, Canada, ⁷Paediatric Critical Care, The University of Western Ontario, London, ON, Canada, ⁸Medicine, The University of Western Ontario, London, ON, Canada, ⁹Medical Imaging, The University of Western Ontario, London, ON, Canada

Evidences support that the new SARS-Cov2 virus has neurological consequences in patients. Using the high resolution and sensitivity of 7T MRI, this study will determine if prolonged cognitive and neurological symptoms in patients recovered from COVID-19 illness are related to brain imaging findings. Six patients with neurological symptoms during their illness and with no respiratory symptoms for at least one month have been recruited to date. Advanced 7T MRI including susceptibility weighted imaging, diffusion tensor imaging, and chemical exchange saturation transfer imaging has been successfully acquired in four subjects with patient recruitment ongoing.

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