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Abstract #1748

Long-term cognitive and neurological Effects of COVID-19 Illness detected by 7T MRI

Helma Heidari1,2, Stephanie Handsor3, Koula Pantazopoulos4, Lauryn Richardson4, Kristy Coleman4, Michael Silverman5, Erin Spicer3, Stephen Pasternak4,6, Luciano Sposato6, Doug Fraser7, Anthony Tang8, Ravi S. Menon1,2, Corey Baron1,2, Michael Jurkiewicz9, Elizabeth Finger4,6, Marko Mrkobrada3, Megan Devlin3, and Robert Bartha1,2
1Robarts research Institute, London, ON, Canada, 2Medical Biophysics, The University of Western Ontario, London, ON, Canada, 3Internal Medicine, The University of Western Ontario, London, ON, Canada, 4Parkwood Institute, London, ON, Canada, 5Infectious Diseases, The University of Western Ontario, London, ON, Canada, 6Clinical Neurological Sciences, The University of Western Ontario, London, ON, Canada, 7Paediatric Critical Care, The University of Western Ontario, London, ON, Canada, 8Medicine, The University of Western Ontario, London, ON, Canada, 9Medical Imaging, The University of Western Ontario, London, ON, Canada

Evidences support that the new SARS-Cov2 virus has neurological consequences in patients. Using the high resolution and sensitivity of 7T MRI, this study will determine if prolonged cognitive and neurological symptoms in patients recovered from COVID-19 illness are related to brain imaging findings. Six patients with neurological symptoms during their illness and with no respiratory symptoms for at least one month have been recruited to date. Advanced 7T MRI including susceptibility weighted imaging, diffusion tensor imaging, and chemical exchange saturation transfer imaging has been successfully acquired in four subjects with patient recruitment ongoing.

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