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Abstract #1788

31P dual-band pulse for selective refocusing of phosphomonoesters and phosphodiesters at low B1+ and low SAR

Zahra Shams1, Evita C. Wiegers1, Wybe J.M. van der Kemp1, Dennis W.J. Klomp1, and Jannie P. Wijnen1
1Department of radiology, University Medical Center Utrecht, Utrecht, Netherlands

The ratio of phosphomonoesters (PME) and phosphodiesters (PDE) is potentially an important biomarker of cancer in the body, which can be measured by 31P MR spectroscopy. Here, we introduce a dual band pulse of low B1+ amplitude for specific refocusing of these metabolite signals. This can be an alternative solution to the high power demanding adiabatic refocusing pulses used for 31P MRS in the body, upon using a multi-echo sequence.

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