Abstract #1788

31P dual-band pulse for selective refocusing of phosphomonoesters and phosphodiesters at low B1+ and low SAR

Zahra Shams¹, Evita C. Wiegers¹, Wybe J.M. van der Kemp¹, Dennis W.J. Klomp¹, and Jannie P. Wijnen¹

¹Department of radiology, University Medical Center Utrecht, Utrecht, Netherlands

The ratio of phosphomonoesters (PME) and phosphodiesters (PDE) is potentially an important biomarker of cancer in the body, which can be measured by ³¹P MR spectroscopy. Here, we introduce a dual band pulse of low B₁⁺ amplitude for specific refocusing of these metabolite signals. This can be an alternative solution to the high power demanding adiabatic refocusing pulses used for ³¹P MRS in the body, upon using a multi-echo sequence.

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