Abstract #1807

Three Dimensional Sodium Magnetic Resonance Fingerprinting using Irreducible Spherical Tensor Operator Simulations

Fabian J. Kratzer¹, Sebastian Flassbeck^1,2,3, Sebastian Schmitter^1,4, Tobias Wilferth⁵, Arthur W. Magill¹, Benjamin R. Knowles¹, Tanja Platt¹, Peter Bachert¹, Mark E. Ladd¹, and Armin M. Nagel^1,5

¹Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ²Center for Advanded Imaging Innovation and Research, New York University, New York, NY, United States, ³Center for Biomedical Imaging, Dept. of Radiology, New York University, New York, NY, United States, ⁴Physikalisch Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, ⁵Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen (FAU), Erlangen, Germany

Sodium relaxation times have been shown to be altered in several diseases. Hence, 2D sodium relaxometry using Magnetic Resonance Fingerprinting (²³Na-MRF) was demonstrated recently as a proof of concept. In this work an extension to a 3D sequence is presented. Furthermore, a more complex signal model based on irreducible spherical tensor operators was investigated. The feasibility of simultaneous 3D quantification of T₁, T_2s^*, T_2l^*, T₂^* and ΔB₀ was demonstrated in phantom measurements.

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