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Abstract #1807

Three Dimensional Sodium Magnetic Resonance Fingerprinting using Irreducible Spherical Tensor Operator Simulations

Fabian J. Kratzer1, Sebastian Flassbeck1,2,3, Sebastian Schmitter1,4, Tobias Wilferth5, Arthur W. Magill1, Benjamin R. Knowles1, Tanja Platt1, Peter Bachert1, Mark E. Ladd1, and Armin M. Nagel1,5
1Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 2Center for Advanded Imaging Innovation and Research, New York University, New York, NY, United States, 3Center for Biomedical Imaging, Dept. of Radiology, New York University, New York, NY, United States, 4Physikalisch Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, 5Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen (FAU), Erlangen, Germany

Sodium relaxation times have been shown to be altered in several diseases. Hence, 2D sodium relaxometry using Magnetic Resonance Fingerprinting (23Na-MRF) was demonstrated recently as a proof of concept. In this work an extension to a 3D sequence is presented. Furthermore, a more complex signal model based on irreducible spherical tensor operators was investigated. The feasibility of simultaneous 3D quantification of T1, T2s*, T2l*, T2* and ΔB0 was demonstrated in phantom measurements.

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