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Abstract #1810

Fast Fluorine Spectroscopic Imaging with pseudo-spiral k-space sampling

Muhammed Yildirim1,2, Patrick Scholtz2, Markus Schütz2, Xenia Kovalyk2, Edwin Heijman2,3, Rolf Lamerichs3, Holger Grüll2, and Esin Ozturk Isik1
1Computational Imaging Lab, Institute Of Biomedical Engineering, Bogazici University, Istanbul, Turkey, 2Institute of Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany, 3Philip Research Labs, Eindhoven, Netherlands

19F-MRI constitutes a viable platform for quantitative theranostics. However, being impaired by physiological absence, and complex NMR spectra of perfluorocarbons, for 19F-MR it is essential to achieve high imaging efficiency. This work introduces a novel spectroscopic imaging sequence, BaSSI, that resides on a balanced psuedo-spiral acquisition scheme and compares against 3D balanced UTE SSFP imaging, that has become the golden standard of fluorine imaging. The work, optimizes both sequences to their fullest, and tests their performance using miniscule samples of PFOB.

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