Abstract #1810

Fast Fluorine Spectroscopic Imaging with pseudo-spiral k-space sampling

Muhammed Yildirim^1,2, Patrick Scholtz², Markus Schütz², Xenia Kovalyk², Edwin Heijman^2,3, Rolf Lamerichs³, Holger Grüll², and Esin Ozturk Isik¹

¹Computational Imaging Lab, Institute Of Biomedical Engineering, Bogazici University, Istanbul, Turkey, ²Institute of Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany, ³Philip Research Labs, Eindhoven, Netherlands

¹⁹F-MRI constitutes a viable platform for quantitative theranostics. However, being impaired by physiological absence, and complex NMR spectra of perfluorocarbons, for ¹⁹F-MR it is essential to achieve high imaging efficiency. This work introduces a novel spectroscopic imaging sequence, BaSSI, that resides on a balanced psuedo-spiral acquisition scheme and compares against 3D balanced UTE SSFP imaging, that has become the golden standard of fluorine imaging. The work, optimizes both sequences to their fullest, and tests their performance using miniscule samples of PFOB.

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