Meeting Banner
Abstract #1814

Conserving low amplitude resonances in tensor rank truncation for image enhancement of spectroscopic imaging data.

Alan J. Wright1, Richard Mair1,2,3, Anastasia Tsyben1, and Kevin M. Brindle1,3,4
1CRUK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom, 2Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom, 3Cancer Research UK Major Centre-Cambridge, University of Cambridge, Cambridge, United Kingdom, 4Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

Tensor decomposition can be used for denoising magnetic resonance spectroscopic imaging (MRSI) data by reconstructing the data from a small number of ranks. Selecting too low an order can remove data from the reconstruction and alter peak amplitudes. A condition for selection of rank order is proposed that removes only noise from the reconstructed data and, therefore, preserves signals from low amplitude resonances. Denoising algorithms that apply this condition are demonstrated for metabolic imaging data sets obtained with hyperpolarised [1-13C]pyruvate and [6,6-2H]glucose in preclinical cancer models, which improve signal-to-noise and reduce the Cramér-Rao lower bound errors in peak fitting.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords