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Abstract #1985

Simultaneous Water and Lipid Suppression Using Chemical Selective Adiabatic Refocusing Pulses Echo Planar Spectroscopic Imaging (EPSI) at 7T

Guodong Weng1, Sulaiman Sheriff2, Claus Kiefer1, Irena Zubak3, Andrew A Maudsley2, and Johannes Slotboom1
1Institute for Diagnostic and Interventional Neuroradiology, Support Center for Advanced Neuroimaging (SCAN), University of Bern, Bern, Switzerland, 2Department of Radiology, University of Miami School of Medicine, Miami, FL, United States, 3Inselspital Bern and University Hospital, Bern, Switzerland

To tackle the chemical shift displacement artifacts (CSDA), B1-inhomoheneity, water and fat suppression as well as specific absorption-rate (SAR) limitation at 7T spectroscopy, an EPSI-variant sequence is developed in this study. The conventional slice-selective refocusing pulse is replaced by a spectral-selective adiabatic 2π-pulse pair. The results show a 77% reduction of CSDA, homogeneous refocusing map, water suppression factor ≥ 1000 within an acceptable SAR both in vitro and in vivo measurement. The scan time for the whole brain is within 8 minutes. This new EPSI-variant sequence shows its high application potential clinical routine.

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