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Abstract #2006

Reproducibility of High-Resolution 1H-MRSI at 7T Using SPICE

Pallab K Bhattacharyya1, Rong Guo2, Yudu Li2, Yibo Zhao2, Zhi-Pei Liang2, and Mark J Lowe1
1Cleveland Clinic Foundation, CLEVELAND, OH, United States, 2University of Illinois, Urbana, IL, United States

Subspace-based rapid high resolution MRSI technique SPICE (SPectroscopic Imaging by exploiting spatiospectral CorrElation) was implemented on Siemens Magnetom 7T scanner. Reproducibility of SPICE at 7T with respect to metabolite measures was evaluated for phantom as well as in vivo scans with 3×3×3 mm3 spatial resolution. A phantom and a healthy subject were scanned twice during the same session, with the healthy subject being scanned on two different days. Strong scan-to-scan metabolite concentration correlations were observed in both phantom and in vivo scans. Good reproducibility was also demonstrated from Bland Altman analysis.

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