Abstract #2082

Lesion Patterns and Blood Flow Lateralization in Atherosclerotic Middle Cerebral Artery Disease

Wenwen Chen¹, Xiaowei Song², Shuo Chen¹, Mingzhu Fu¹, Hanyu Wei¹, Duoduo Hou², Le Chen², Miaoqi Zhang¹, Jian Wu², and Rui Li¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, ²Beijing Tsinghua Changgung Hospital, Beijing, China

Intracranial atherosclerosis disease (ICAD) can induce blood flow lateralization (BFL). However, the relationship of infarct patterns (IPs) with BFL was rarely explored. This study investigated the relationship between BFL and IPs in middle cerebral artery (MCA) using 4D flow MRI. Twenty-eight patients with unilateral MCA infarction were included. Average net flow (Flow_avg) of infarction side and the contralateral side of MCA-M1 were compared in various IPs. Flow_avg is significantly different between two sides of MCA in cortical infarct, but not significant in subcortical lesions. This suggests that cortical infarct may be the specific pattern for BFL in MCA.

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