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Abstract #2082

Lesion Patterns and Blood Flow Lateralization in Atherosclerotic Middle Cerebral Artery Disease

Wenwen Chen1, Xiaowei Song2, Shuo Chen1, Mingzhu Fu1, Hanyu Wei1, Duoduo Hou2, Le Chen2, Miaoqi Zhang1, Jian Wu2, and Rui Li1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2Beijing Tsinghua Changgung Hospital, Beijing, China

Intracranial atherosclerosis disease (ICAD) can induce blood flow lateralization (BFL). However, the relationship of infarct patterns (IPs) with BFL was rarely explored. This study investigated the relationship between BFL and IPs in middle cerebral artery (MCA) using 4D flow MRI. Twenty-eight patients with unilateral MCA infarction were included. Average net flow (Flowavg) of infarction side and the contralateral side of MCA-M1 were compared in various IPs. Flowavg is significantly different between two sides of MCA in cortical infarct, but not significant in subcortical lesions. This suggests that cortical infarct may be the specific pattern for BFL in MCA.

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