Abstract #2095

A small-vessel MRI phantom for quantitative analysis of diffusion-weighted images: a validation study with numerical computation

Hajime Tamura¹, Hideki Ota², Tatsuo Nagasaka³, Ryuichi Mori³, Chihiro Kato¹, Kohsuke Gonda¹, and Kenichi Funamoto⁴

¹Department of Medical Physics, Tohoku University, Graduate school of medicine, Sendai, Japan, ²Department of Advanced MRI Collaboration Research, Tohoku University, Graduate school of medicine, Sendai, Japan, ³Department of Radiology, Tohoku University hospital, Sendai, Japan, ⁴Institute of Fluid Science, Tohoku University, Sendai, Japan

We designed a 3-dimensional unicursal channel phantom to simulate small vessels and obtained diffusion-weighted images with varying infusion rate of water. The signal intensities were compared with theoretical data by numerical computation. Our model will allow for understanding the behavior of IVIM images under various flow conditions and evaluating performance of MRI platforms.

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