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Abstract #2095

A small-vessel MRI phantom for quantitative analysis of diffusion-weighted images: a validation study with numerical computation

Hajime Tamura1, Hideki Ota2, Tatsuo Nagasaka3, Ryuichi Mori3, Chihiro Kato1, Kohsuke Gonda1, and Kenichi Funamoto4
1Department of Medical Physics, Tohoku University, Graduate school of medicine, Sendai, Japan, 2Department of Advanced MRI Collaboration Research, Tohoku University, Graduate school of medicine, Sendai, Japan, 3Department of Radiology, Tohoku University hospital, Sendai, Japan, 4Institute of Fluid Science, Tohoku University, Sendai, Japan

We designed a 3-dimensional unicursal channel phantom to simulate small vessels and obtained diffusion-weighted images with varying infusion rate of water. The signal intensities were compared with theoretical data by numerical computation. Our model will allow for understanding the behavior of IVIM images under various flow conditions and evaluating performance of MRI platforms.

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