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Abstract #2105

Hepatocellular Adenoma: Radiology-Pathology Subtype Associations with Hepatobiliary Phase MRI

Alix C Hopp1, Carolyn Mead-Harvey2, and Alvin C Silva1
1Radiology, Mayo Clinic Arizona, Phoenix, AZ, United States, 2Mayo Clinic Arizona, Phoenix, AZ, United States

Hepatocellular adenoma (HCA) is an uncommon benign tumor with risk for tumoral hemorrhage and malignant transformation. At least four HCA subtypes have been described: Inflammatory (I-HCA); hepatocyte nuclear factor 1-α mutated (H-HCA); β-catenin (B-HCA); and unclassified (U-HCA). I-HCA has the highest risk for tumoral hemorrhage, whereas B-HCA is the most likely to undergo malignant transformation. Clinical management differs for HCA subtypes, based on their different level of risk for complications. This study examines the image findings of pathologically proven HCAs from our institution on gadoxetic acid-enhanced MRI, in order to describe association between MRI image findings with HCA subtypes.

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