Abstract #2128

Diffusion kurtosis imaging (DKI) for predicting Ki-67 expression in hepatocellular carcinoma

Qiying Ke¹, Tianyuan Zhang², Xuan Jin¹, Xinming Li¹, Yingjie Mei³, and Xianyue Quan¹

¹Department of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, China, ²Department of Radiology, Foshan First People's Hospital, Foshan, China, ³Philips Healthcare, Guangzhou, China

Diffusion kurtosis imaging (DKI) is a promising non-invasive method for evaluating the expression of Ki-67, a marker of cellular proliferation in HCC, which may contribute to predict recurrence and prognosis preoperatively. In this study, we evaluated the potential role of DKI in preoperative prediction of Ki-67 expression in HCC. The results show that increased MK and decreased ADC values are potential predictive biomarkers for of Ki-67 expression of in HCC.

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