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Abstract #2132

Gradient non-linearity correction in liver DWI using motion compensated diffusion encoding waveforms

Sean McTavish1, Anh T. Van1, Johannes M. Peeters2, Kilian Weiss3, Marcus R. Makowski1, Rickmer F. Braren1, and Dimitrios C. Karampinos1
1Department of Diagnostic and Interventional Radiology, Technical University of Munich, Munich, Germany, 2Philips Healthcare, Best, Netherlands, 3Philips Healthcare, Hamburg, Germany

Despite its strong clinical significance in lesion detection and tumor staging, liver DWI remains challenged by its strong sensitivity to motion effects. Motion-compensated diffusion encoding schemes have been recently proposed to improve DW liver signal homogeneity especially in the left liver lobe, a region typically affected by cardiac motion. In addition, a simplified gradient non-linearity correction scheme has been proposed for usage with standard pulsed gradient spin echo (pgse) diffusion encoding waveforms. The present work investigates the usage of this gradient nonlinearity correction algorithm with different motion compensated diffusion encoding gradient waveforms in the context of coronal ADC mapping in the liver.

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