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Abstract #2248

Quantitative susceptibility mapping of the brain in neonates and infants

Sayo Otani1, Yasutaka Fushimi1, Satoshi Nakajima1, Akihiko Sakata1, Takuya Hinoda1, Sonoko Oshima1, Krishna Pandu Wicaksono1, Hiroshi Tagawa1, Yang Wang1, and Yuji Nakamoto1
1Kyoto University Graduate School of Medicine, Kyoto, Japan

We evaluated magnetic susceptibility of the brain in 202 neonates and infants. We manually placed volumes of interest of the caudate nucleus, globus pallidus, putamen and ventral posterior lateral nucleus of the thalamus in the MNI space. Our study showed that elevation of magnetic susceptibility probably associated with iron deposition of the basal ganglia and thalamus increased with chronological age from birth to 2 years using volume-of-interest analysis.

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