Abstract #2324

Comparison of MR values at 3T and 14T in a mouse model of pancreatic ductal adenocarcinoma.

Ravneet Vohra¹, Yak-Nam Wang², Helena Son³, Stephanie Totten², and Donghoon Lee¹

¹Radiology, University of Washington, Seattle, WA, United States, ²Applied Physics Laboratory, University of Washington, Seattle, WA, United States, ³Gastroenterology, University of Washington, Seattle, WA, United States

Pancreatic cancer is expected to become the second leading cause of the cancer related deaths in the USA by 2020. The goal of all pre-clinical magnetic resonance imaging (MRI) studies is to translate the pre-clinical MR values to the clinical scanners and ultimately to human population. MRI has been proven to be extremely useful in clinical trials for monitoring tumor development and assessing therapeutic effects of novel therapeutic strategies. The aim of this study was to measure (T2) relaxation time and magnetization ratio (MTR) in a mouse model of pancreatic ductal adenocarcinoma (PDA) at pre-clinical (14T) and clinical (3T) scanner.

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