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Abstract #2330

Feasibility of quantitative T2 mapping imaging in the diagnosis and chemotherapy response tracking of rectal cancer

Yunxing Tang1, Ailian Liu1, Jiazheng Wang2, Zhiwei Shen2, Yunsong Liu1, Yuhui Liu1, Anliang Chen1, and QingWei Song1
1The First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Philips Healthcare, Beijing, China

Clinical diagnosis and real-time evaluation of chemotherapy response for rectal cancer remain challenging due to the lack of effective non-invasive examinational means. The quantitative T2 mapping technique is an effective method for MRI relaxometry in tissues. In this study, we demonstrated that T2 values were significantly higher in rectal cancer than those in the healthy rectal wall, and significantly increased after chemotherapy. Therefore, quantitative T2 mapping might be a promising non-invasive method in the diagnosis and chemotherapy response tracking of rectal cancer.

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