Abstract #2338

Free-breathing T1 Mapping of the Whole Liver Using GOAL-SNAP Sequence in Patients with Hilar Cholangiocarcinoma

Yajie Wang¹, Ming Xiao², Canhong Xiang², Yuewei Zhang², Haikun Qi³, Yishi Wang⁴, Jiahong Dong², and Huijun Chen¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, ²Hepato-pancreato-biliary Center, Beijing Tsinghua Changgung Hospital, School of Medicine, Tsinghua University, Beijing, China, ³School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ⁴Philips Healthcare, Beijing, China

T1 mapping combined with MR contrast agent administration has been applied to evaluate the liver function. However, conventional liver T1 mapping techniques have some limitations, such as the need of breath-holding, limited slice coverage or the need of multiple acquisitions. In this study, a free-breathing whole liver T1 mapping technique was proposed using a single scan. Preliminary results in patients with HCCA demonstrated its great potential for T1 quantification of the liver and liver function estimation.

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