Abstract #2387

Temperature dependence of T1 and T2 values in formalin-fixed brains

Masatoshi Kojima^1,2, Yohsuke Makino^1,3, and Hirotarou Iwase^1,3

¹Department of legal of medicine, graduate school of medicine, Chiba university, Chiba, Japan, ²Department of radiology, Chiba medical center, Chiba, Japan, ³Department of forensic medicine, graduate school of medicine, Tokyo university, Tokyo, Japan

The purpose of this study was to investigate the variation of cerebral temperature and T1 and T2 values by varying the temperature of the formalin-fixed brain, assuming various temperatures during postmortem MRI. The T1 and T2 values were calculated by varying the temperature of the formalin-fixed brain in a thermostatic bath from 5°C to 40°C. THe T2 value prolonged with increasing temperature, and the T1 value was highest at 20°C and decreased at lower and higher temperatures. The results of this study will be useful for setting conditions for postmortem MRI imaging and image interpretation.

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