Abstract #2451

Multi-band in Diffusion MRI: Can we go too fast?

Arun Venkataraman¹, Benjamin Risk², Deqian Qiu^3,4, Jianhui Zhong^1,5, and Zhengwu Zhang⁶

¹Physics and Astronomy, University of Rochester, Rochester, NY, United States, ²Biostatistics and Bioinformatics, Emory University, Atlanta, GA, United States, ³Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States, ⁴Biomedical Engineering, Emory University, Atlanta, GA, United States, ⁵Imaging Sciences, University of Rochester Medical Center, Rochester, NY, United States, ⁶Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY, United States

In this study, we sought to better understand the effect of multiband and phase acceleration on diffusion image reconstruction. As part of an on-going study on SMS in dMRI, 10 test-retest scans from 5 young, healthy subjects were scanned. We found that g-factor, reflecting noise amplification, increased with higher acceleration factors, the g-factor was also higher in frontal regions compared to occipital regions. We also found that the DTI fitting performed worse where we saw increased g-factor. Finally, we found that streamlines were stable as a function of acceleration in the occipital areas, but not frontal areas.

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