Ellipsoidal tensor encoding (ETE) with independent control of spectral anisotropy (SA) and tuning provides two distinct encoding frequency windows in a single experiment and yields distinctly different signal signatures for compartments with different anisotropic time-dependent diffusion. ETE can be orientation invariant, depending on SA and restriction geometry. Signal orientation variation minima depends on size relative to tuning but not on orientation dispersion. This popery could be useful for quick size estimation and geometry detection. Such encoding strategy could potentially provide new contrasts sensitive to specific pathological variations.
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