Abstract #2513

A Simple, Multi-purpose Coil for Improved Mouse Brain Image Quality and Coverage at 3-T MRI

Kuan-Hung Cho¹, Po-Hsun He¹, Hsuan-Han Chiang¹, Ming-Jye Chen¹, Ezequiel Farrher², Nadim Jon Shah^2,3, Chang-Hoon Choi², and Li-Wei Kuo^1,4

¹Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli County, Taiwan, ²Institute of Neuroscience and Medicine – 4, Forschungszentrum Juelich, Juelich, Germany, ³Department of Neurology, Faculty of Medicine, RWTH Aachen University, Aachen, Germany, ⁴Institute of Medical Device and Imaging, National Taiwan University College of Medicine, Taipei, Taiwan

For mouse brain imaging, determining the size of a loop coil is a trade-off between SNR and imaging coverage. Here, we propose a multi-purpose coil arrangement incorporating a small loop coil and a position-adjustable add-on saddle coil to enhance the imaging coverage of anatomical images and improve the SNR in the regions distant to the surface coil. The result shows the imaging coverage can be adjustable for targeting different brain regions and demonstrated this design concept in mouse brain imaging experiments.

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