Abstract #2520

Repeatability of multi-parametric renal MRI biomarkers in healthy subjects: An iBEAt pilot study

Kanishka Sharma¹, Bashair Alhummiany², David Shelley^2,3, Margaret Saysell^2,3, Maria-Alexandra Olaru⁴, Bernd Kühn⁴, Julie Bailey³, Kelly Wroe³, Cherry Coupland³, Michael Mansfield³, and Steven Sourbron¹

¹Department of Imaging, Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom, ²Department of Biomedical Imaging Sciences, University of Leeds, Leeds, United Kingdom, ³Leeds Teaching Hospitals, Leeds, United Kingdom, ⁴Siemens Healthcare GmbH, Erlangen, Germany

The iBEAt study MRI biomarker panel has been developed to determine if imaging biomarkers can improve predictions of renal function decline in diabetic kidney disease. The aim of this pilot study was to inform the approach to quality control and image processing of iBEAt data. Repeatability in 5 healthy volunteers (4 scans per subject) was analysed with a prototype image-processing pipeline. The results indicated that repeatability of renal T₁, T₂* and phase-contrast renal blood flow was comparable to literature, and measurement precision was sufficient to detect differences between volunteers. ASL had poor repeatability presumably from B₀ inhomogeneities in labelling plane.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.