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Abstract #2598

Accelerated Chemical Exchange Saturation Transfer Acquisition by Joint K-space and Image-space Parallel Imaging (KIPI)

Zu Tao1, Sun Yi2, Wu Dan1, and Zhang Yi1
1Key Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China, 2MR Collaboration, Siemens Healthcare Ltd., Shanghai, China

The clinical use of chemical exchange saturation transfer (CEST) imaging is limited by its relatively long scan time, because it typically acquires multiple saturation image frames. Here, a novel auto-calibrated reconstruction method by joint k-space and image-space parallel imaging (KIPI) is proposed for faster CEST acquisition. By under-sampling CEST image frames with variable acceleration factors, KIPI allows an acceleration factor of up to 8-fold for acquiring source images, yielding a net speed-up of 6-fold in scan time, and produces image quality close to that of the ground truth.

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