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Abstract #2637

Isovolumic Relaxation Time and e' Metrics Evaluated by Deep-learning Analysis of Long-axis Cine: Correlations to Atrial Pressure and Fibrosis

Dana Peters1, Jérôme Lamy1, Felicia Seemann2, Einar Heiberg3, and Ricardo Gonzales1
1Yale Unversity, New Haven, CT, United States, 2National Institutes of Health, Bethesda, MD, United States, 3Lund University, Lund, Sweden

Using a deep-learning tool for tracking the left ventricular valve plane on long-axis cine, markers of diastolic dysfunction could be easily evaluated, including e-prime, a-prime (atrial kick valve velocity), s-prime, and isovolumic relaxation time (IVRT). This analysis, performed in 23 patients with atrial fibrillation, revealed a dependence of both a-prime and IVRT on atrial fibrosis.

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