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Abstract #2649

Identification of Hemodynamic Biomarkers for Bicuspid Aortic Valve Patients using Machine Learning

Pamela Franco1,2,3, Julio Sotelo1,3,4, Lydia Dux-Santoy5, Andrea Guala5, Aroa Ruiz-Muñoz5, Arturo Evangelista5, José Rodríguez-Palomares5, and Sergio Uribe1,3,6
1Biomedical Imaging Center, School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 2Electrical Engineering Department, School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 3Millennium Nucleus for Cardiovascular Magnetic Resonance, Santiago, Chile, 4School of Biomedical Engineering, Universidad de Valparaíso, Valparaíso, Chile, 5Department of Cardiology, Hospital Universitari Vall d’Hebron, Vall d’Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain, 6Radiology Department, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile

The clinical significance and economic burden of bicuspid aortic valve (BAV) disease justify the need for improved clinical guidelines and more robust therapeutic modalities. Recent advances in medical imaging have demonstrated the existence of altered hemodynamics in these patients. To identify hemodynamic biomarkers for BAV patients, we present a machine learning method consisting of a feature selection mechanism to classify healthy volunteers and BAV patients accurately.

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