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Abstract #2666

AI-based Computer-Aided System for Cardiovascular Disease Evaluation (AI-CASCADE) for carotid tissue quantification

Yin Guo1, Li Chen2, Dongxiang Xu3, Rui Li4, Xihai Zhao4, Thomas S. Hatsukami5, and Chun Yuan1,3
1Bioengineering, University of Washington, Seattle, WA, United States, 2Electrical Engineering, University of Washington, Seattle, WA, United States, 3Radiology, University of Washington, Seattle, WA, United States, 4Biomedical Engineering, Tsinghua University, Beijing, China, 5Surgery, University of Washington, Seattle, WA, United States

The tissue composition of carotid atherosclerotic plaques is crucial for cardiovascular risk assessment and can be quantified with high-resolution multi-contrast MRI by expert reviewers. The purpose of this work is to develop AI-CASCADE, a fully automated solution for quantitative analysis of carotid MRI, including artery localization, vessel wall segmentation, artery registration and plaque component segmentation. Results in our preliminary study show that AI-CASCADE achieves good agreements with manual results and has great potential as an efficient and reliable clinical tool.

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